Acute Myeloid Leukemia

AML Leukemia, Acute Leukemia, symptoms, prognosis, survival rate

20 Aug

Living with AML Leukemia

Posted in AML Leukemia on 20.08.13 by Merlyn

acute leukemia

acute leukemia

Coping with AML Leukemia can be quite challenging and difficult emotionally, mentally, and physically. To others, having Acute Myeloid Leukemia Stages can even test their spirituality. AML Leukemia can affect every aspect of your life and of those around you. That’s why treatment should be sought as soon as possible.

Initially, when you get diagnosed with AML Leukemia, you might feel very confused, frightened, and upset. An overwhelming feeling of not being in control will take place. Knowing and understanding the right kind of information is vital to one’s survival, as people who are very well informed about their illness and what they’re going through are more able to make decisions with a clear mind and to cope more easily.

Coping Physically

When being treated, you will experience a lot of physical changes, and problems on, and within, your body. They should improve after the treatment plan is done. One of the most common things that arise is tiredness, which could continue for several more months after treatment.

Hair Loss

People find it difficult to cope with losing hair, but don’t worry, your hair will grow back within a few weeks after the treatment is over. However, changes in hair texture and color may be apparent, compared to how they were before getting the treatment.

Skin

If you went through body irradiation, your skin will be more sensitive, and the heat of the sun might become a little bit unbearable. There are skin products that could take care of this.

Practical Coping

You will need to learn how to manage life practically. Children, work, money and a lot of other things can become an issue. Who would you tell that you have AML? How would you find the right words to say? Who will take care of your children?

Remember, everything takes time and each issue will be sorted out easily if you put your mind into it. There are specially trained people leading support groups of those with cancer. Inform your doctor or nurse about what troubles you, and they will direct you to these groups. These people will help you emotionally, and in the process, will also help stabilize your state of mind.

Coping Emotionally of AML Leukemia Survivors

The AML Leukemia journey can really break a person. There are feelings of loneliness, uselessness, and helplessness to face. The encouraging news is, you don’t need to do it alone. Not informing your family or friends could make them feel that you are shutting them out of your life. Let them in and open up to them, as you will need all the help that you can get.

Get into support groups, learn more about your disease, and get to know other people who have it. Maybe you can’t modify the fact that you have cancer, but you can change your view about it and how you will live your life. And that’s by making healthy choices, taking care of your body more, and having an uncluttered mind.

Keep thinking about the future and don’t dwell too much on the problem. Humor is a great medicine for getting by. Don’t forget to relax because worrying about Acute Myeloid Leukemia does nothing about your situation, and can only worsen your overall health even more.

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19 Aug

Can You Prevent AML Leukemia?

Posted in AML Leukemia on 19.08.13 by Merlyn

aml leukemia prevention

As of the moment, there is no known, definite cause of AML Leukemia, and as such, there is currently no way of preventing it from developing. While scientists know that Acute Myeloid Leukemia Symptoms occurs more in males than in females, and more frequently in Caucasians than African-Americans, scientists can’t explain how one person can get acute leukemia, while another does not.

Some people with Acute Leukemia have one or more known risk factors, others do not. Even if a person has more than one risk factor, it is still impossible to tell what actually caused the cancer to begin with. By learning more about AML Leukemia, researchers are hopeful to at least better understand what the causes are, and how to prevent the disease from happening.

Genetic and Non-Genetic Factors

The chance of an individual developing Acute Myeloid Leukemia depends on both genetic and non-genetic risk factors. A genetic factor is inherited, while a non-genetic factor focuses more on a person’s lifestyle and environment.

Currently, there’s nothing we can do for the genetic factors. However, for non-genetic factors, there are certain risk factors that can be avoided. In the US alone, two-thirds of cancer deaths are linked to a poor diet, obesity, tobacco use, and a lack of exercise.

Lifestyle

Since lifestyle risk factors are based on what we do and not on what we are, these factors are very modifiable. Nevertheless, lifestyle changes for the opportunity to prevent cancer is still very much under-appreciated by many people.

Diet

Having a healthy and proper diet can decrease the risk of developing AML Leukemia. Numerous studies have shown a wealth of often contradictory information about the protective factors and detrimental effects of different kinds of food.

There is convincing evidence excessive body fat can lead to an increased risk in many types of cancer including Acute Myeloid Leukemia. To avoid excess fat, it is recommended to limit caloric intake, or at least, to balance caloric intake with enough exercise. Numerous fruits and vegetables have been associated with the reduced risk of developing at least 10 different kinds of cancers. Vitamins that are contained within these healthy produce are often referred to as antioxidants.

Exercise

With higher and more levels of physical activity, the chances are greater for lowering cancer risk.

Smoking

Smoking is the most significant and controllable risk factor for Stages Acute Myelogenous Leukemia. In fact, quitting smoking offers the greatest chance to avoid any types of cancer related diseases and other types of illnesses.

Environment

Most experts agree that workplaces that present long term exposure to chemical compounds, such as benzene and other solvent products, are linked to developing Early Symptoms Leukemia. However, only a small portion are accounted for in leukemia cases. Just the same, avoiding long term exposures to chemicals can lower risk factors.

Screening AML Leukemia Symptoms

Regular screening, such as certain examinations and tests that will evaluate a person’s health could provide early detection which can possibly lead to better and successful treatment plans.  Scientists and researchers, up to now, continue to study certain characteristics that can be associated with increased risk factors for AML Leukemia, targeting more effective prevention, early detection, and a better treatment strategy for the disease, as a whole.

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18 Aug

AML Leukemia Treatment Options

Posted in AML Leukemia on 18.08.13 by Merlyn

acute leukemia treatment

There are numerous ways to treat AML Leukemia.  There is the standard treatment, which is the mode of treatment currently used, and then there are the clinical trials.

Clinical Trials of Acute Leukemia Symptoms

Patients thinking of undergoing Clinical Trials should give themselves ample time to think about whether they want to undergo such form of treatment.  Like the Standard Forms of treatment, Clinical Trials do not guarantee a hundred percent success rate and may even be lower than that of Standard Forms of treatment.  Nonetheless, some patients have undergone Clinical Trials and went on to improve modern treatment but, not everyone can undergo Clinical Trials.

Some are only open to those who have not yet been administered any type of treatment. If and when successful, Clinical Trials go on to become part of Standard forms of treatment.

To better understand how patients are treated, we need to understand that AML Leukemia has two phases of treatment. These are:

  1. Remission Induction Therapy
  2. Post-Remission Therapy

The first phase aims to put the leukemia into remission by eliminating leukemia cells in the bone marrow and in the blood. The second phase is a follow up treatment that aims to eliminate any remaining leukemia cell in the blood or in the bone marrow which could either be at work or is inactive; preventing it to once again multiply that may cause the patient to go into a relapse.

Standard Form Treatment

The four ways of treating a patient of Acute Myeloid Leukemia Symptoms via Standard form are as follows:

  • Chemotherapy
  • Stem Cell Transplant
  • Radiation Therapy
  • Other types of anticancer drugs

Chemotherapy is a drug dependent form of treatment and is administered by mouth or is injected into a vein or a muscle, preventing cancer cells from growing or dividing any further.

Stem Cell therapy, on the other hand is a follow up treatment given after undergoing Chemotherapy, by removing the patient’s abnormal cells and replacing them with new ones (immature blood cells), these newly infused stem cells will help restore the body’s blood cell.

Using high-energy X-ray is a form of Radiation Therapy, a treatment that also aims to eliminate cancer cells or to at least prevent them from re-growing.  There are two sub-types of Radiation Therapy, one is External Radiation, a machine based treatment that sends radiation to the body to kill off cancer cells. The other is Internal Radiation, a treatment that uses needles, seeds and others of the like that contains radioactive substances which also aims kill cancer cells.

Another form of treatment is the use of anticancer drugs such as Arsenic Trioxide and All-trans Retinoic acid to kill off leukemia cells, stop them from growing, or to aid leukemia cells in order for them to turn into white blood cells.  These type of drugs are also a form of treatment for Acute Promyelocytic Leukemia, a subtype of Acute Myeloid Leukemia.

Though these treatments exist, none have been proven to come up with a hundred per cent chance of curing the disease. These includes the performance of Clinical trials. Likewise, none are a hundred percent safe, thus such treatments may or may not yield positive results for every patient with AML Leukemia.

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17 Aug

Stages of AML Leukemia

Posted in AML Leukemia on 17.08.13 by Merlyn

aml leukemia stages

aml leukemia stages

There is currently no standard way or system to determine what stage of AML Leukemia a patient is in. However Acute Leukemia is sometimes staged in accordance with what type of cell is involved, and what it looks like under a microscope. This is referred to a  the French-American-British classification system. The disease is classified as untreated, in remission, and recurrent.

What to Look for

In untreated adult AML Leukemia patients, the patient is newly diagnosed and has not been given any form of treatment for the disease. Patients can however be given medications for fever, bleeding and pain, which is standard procedure.

Note the following in this pseudo-stage:

  • Abnormal  (complete blood count). CBC range varies and differs between men and women.
  • Cells in the bone marrow are at least 20% leukemia cells.
  • Symptoms of leukemia are showing.

Patients who are in remission, or those who show a temporary end of signs or symptoms regarding a disease that may re-occur,  are being given treatment and are showing the following signs:

  • No abnormalities in the CBC or complete blood count.
  • There is 5% or less leukemia cells in the bone marrow.
  • Patient is not showing any form or sign and symptom of leukemia in the brain or in any part of the body.
  • Even though treatments and medications are given to Acute Myeloid Leukemia in Adults patients, re-occurrence of the treated disease is not uncommon and may return in the blood or in the bone marrow.
  • The extent of the cancer – if it has spread outside the blood or the bone marrow – is a determining factor on how treatment is to be planned. Tests like the CT Scan, lumbar puncturing, and ultrasound exams are administered as a way to determine the extent of the cancer.

Factors that Can Affect Prognosis and Acute Myeloid Leukemia Stages

  • Advanced age – this may negatively affect the prognosis of leukemia
  • Any history of blood disorder prior to the leukemia
  • Chromosome mutations or abnormalities
  • Enlarging of organs such as the liver or the spleen
  • Metastasis -  the formation and spread of tumors. There are three possible ways that these cancer cells can spread in your body:
  1. Through the blood – a solid tumor may form if the cancer cells travel through the blood and then start invading solid tissues in the body.
  2. Through the lymphatic system – if the cancer manages to enter the lymphatic system and travels across the lymphatic vessels, then solid tumors may form across the body.
  3. Through solid tissues – affected tissues that have formed a solid tumor may also be seen to have spread throughout their surrounding area.

There are times that AML Leukemia cannot be traced using standard testing such as looking at a cell under a microscope. However, through a more sensitive type of testing possibly PCR, or Flow Cytometry, there is a possibility of finding evidence that the leukemia cells are still present in the bone marrow.

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16 Aug

AML Leukemia Diagnosis and Tests

Posted in AML Leukemia on 16.08.13 by Merlyn

aml leukemia prognosis

If you feel that you have the symptoms of AML Leukemia, then your doctor may recommend that you undergo a battery of diagnostic tests.

Diagnostic Tests for AML Leukemia

Physical Exam and History

The attending doctor will check the patient’s medical history (i.e. past illnesses) and personal background (i.e. patient’s health habits) to see general signs that may be attributed to the development Acute Myeloid Leukemia Symptoms. A physical exam will thoroughly check for signs of disease (i.e. lumps, or anything that might seem unusual).

Blood Tests

Most people with Acute Myeloid Leukemia Stages have too many WBCs (white blood cells), and not enough RBCs (red blood cells) and platelets. The presence of a “blast” or immature cells (normally found in the bone marrow and which do not circulate in the bloodstream) is an indicator that you might have AML.

Bone Marrow Test

Since a blood test can suggest leukemia, it usually takes a bone marrow test to confirm the diagnosis. When a bone marrow biopsy takes place, a needle is used to remove a sample of your bone marrow. The sample is usually from your hipbone. Further testing in a laboratory would confirm the diagnosis.

Lumbar Puncture (Spinal Tap)

For some patients removing some fluid from your spinal cord is necessary to check for leukemia cells. The fluid is collected via insertion of a small needle into your spinal canal, which is found in your lower back.

Complete Blood Count

This is a procedure that takes samples of the patient’s blood to be checked for:

  • Number of RBCs, WBCs, and Platelets
  • Amount of Hemoglobin (an oxygen carrying protein) in the red blood cells

A portion of the red blood cells taken from the sample will be used for further testing.

Blood Chemistry Studies

This is a procedure in which the patient’s blood sample is measured to check the amounts of different substances that are released in the body by the organs and the tissues. If the number is too high, or lower than normal, it can be a sign of an underlying disease in the organ or tissue that has it.

Peripheral Blood Smear

This is a procedure in which samples of blood are checked for any presence of blast cells, the number and the kind of WBCs, and the number of platelets. It is also used to check if there are any changes in the RBCs.

Bone Marrow Aspiration and Biopsy

This is a procedure wherein the bone marrow, blood, and a tiny piece of bone are removed via a hollow needle through the hipbone or breastbone. A pathologist scans the samples and checks for signs of cancer.

Cytogenetic Analysis

This is a test to confirm the cells in a sample blood or bone marrow, viewed under a microscope, to  see whether or not there have been changes in the chromosomes.

Reverse Transcription

This is a laboratory test where cell samples of a tissue are studied with chemicals mixed in, to find certain changes in the gene’s function. This a test that is often used to diagnose APL or “Acute Promyelocytic Leukemia.”

Immunophenotyping

This is a  procedure used to identify cells via the types of antigens or markers on its surface. This is a process that’s often used to diagnose the subtype of AML Leukemia by comparing normal cells to affected cancer cells found in the immune system.

When your doctor verifies that you do have Acute Myeloid Leukemia Stages, further testing may happen to determine the extent of the cancer and classify it to a more specific type of AML subtype. Your AML Leukemia subtype is one of the factors in determining which kind of treatment or procedure should be taken.

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15 Aug

Who is at Risk for AML Leukemia?

Posted in AML Leukemia on 15.08.13 by Merlyn

acute leukemia risk

A risk factor is something that affects the chance of catching or developing a disease, such as AML Leukemia. Risk factors do not confirm that you will get or develop a certain disease and even if a person has lots of risk factors and develops a disease, it is often hard to verify what contributed to the development of the disease.

Risk Factors of Acute Myeloid Leukemia Symptoms

Here are  some of the known risk factors for AML Leukemia or Acute Myeloid Leukemia:

  • Smoking – This is the only lifestyle related risk factor that’s linked to AML Leukemia. It is common knowledge that smoking is directly linked to lung cancer, throat cancer, and other diseases. However, a few realize that it also affects the cells that do not come in direct contact with smoke. Tobacco has cancer-causing substances that are absorbed by the lungs and spread through the body by entering the bloodstream.
  • Chemical Exposure – There’s an increased risk for certain cases of chemical exposures. Long term exposure to very high levels of Benzene, a component derived from coal and petroleum, a solvent that’s heavily used in the rubber industry, as well as chemical plants, gasoline-related industries, oil refineries and others, may present a very high risk factor for AML. Benzene is also present in cigarette, cleaning products, glues, detergents and paint strippers.
  • Cancer Treatment – Patients who underwent chemotherapy are more likely to develop Acute Leukemia . Drugs called alkylating agents, as well as platinum agents, have an increased risk of developing Acute Myeloid Leukemia in Adults. This has a peak of about 8 years after chemotherapy. A patient will develop myelodysplastic syndrome before developing Acute Leukemia. Chemo drugs, also known as topoisomerase II poisons are linked to AML.  AML is only likely to occur years after treatment, and without first developing myelodysplastic syndrome.
  • Radiation exposure – Exposure to very high dosage of radiation (for  instance, the survivors of the Bombing of Nagasaki and Hiroshima, and the Chernobyl Disaster), have an increased risk of acquiring AML. Using radiation treatment to battle cancer also poses an increased risk for developing the condition. The possible risk of low exposures to low dosage radiations, such as that of X-rays or CT scans, are not yet well-defined.
  • Blood Disorders – Certain blood disorders have been linked to an increased risk of developing AML. These include chronic diseases such as essential thrombocythemia,  idiopathic myelofibrosis, and polycythemia vera. Treating these diseases with radiation and chemo drugs also increases the risk. Patients who have myelodysplastic syndrome may develop AML as well.
  • Genetics – Genetic mutations present at birth may result in an increased risk of AML Leukemia such as:
    • Ataxia-Telangiectasia
    • Blackfan-Diamond Syndrome
    • Bloom Syndrome
    • Down Syndrome
    • Fanconi Anemia
    • Kostmann Syndrome
    • Li-Fraumeni Syndrome
    • Neurofibromatosis I
    • Schwachman Syndrome
    • Trisomy 8
  • Family History – Being closely related (a parent or sibling) with person that has AML increases the risk of developing AML Leukemia as well. Having an identical twin that developed AML before turning a year old poses a very high risk.
  • Gender – Men have a higher risk than women.

Other possible risks include:

  • exposure to electromagnetic fields
  • herbicides or pesticides
  • other types of chemical solvents

Note that as of the moment, there has been no conclusion on whether these “other risks” are directly linked to developing AML Leukemia as research is still being done  about it.

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14 Aug

Signs and Symptoms of AML Leukemia

Posted in AML Leukemia on 14.08.13 by Merlyn

aml leukemia symptoms

aml leukemia symptoms

General signs and symptoms of AML Leukemia or Acute Myeloid Leukemia in its early states can sometimes mimic those of the common cold or other common diseases. Signs and symptoms may vary from one case to another.

General Symptoms

Fatigue, fever and continual infection, weight loss, night sweats, and easily bleeding after an injury, are some of the common warning signs and symptoms. Here are other symptoms that may be observed or reported. Note that these may usually occur during various stages of the disease:

  • Pale Skin
  • Petechiae (flat, pinpoint spots under the skin caused by bleeding).
  • Enlargement of spleen
  • Enlargement of lymph nodes, in some cases
  • Inflammation of the skin, in some cases
  • Joint /bone pain
  • Swelling of gums
  • Chest pain or shortness of breath
  • Pain with urinating
  • Diarrhea, occasionally
  • Tumor outside bone marrow, in rare cases

AML Leukemia Symptoms in Children

In children, the following are among the most common symptoms and signs that can be recognized:

  • Feeling of tiredness and lethargy due to anemia
  • Bruises and bleeding
  • Infections
  • Aches and pains
  • Swollen lymph glands
  • Loss of Appetite
  • Runny nose
  • Cough

AML Leukemia makes people sick by interfering with the normal bone marrow function. The cells that are affected replace and expel the normal cells out of the bone marrow. This causes low blood cell counts.

Similarity with Some Symptoms of Anemia

The condition of having an insufficient number of red blood cells is commonly called as “anemia” which causes a person to be very pale and tired.  And with a lowered number of WBCs or white blood cells, there is an increased risk of getting an infection.

Anemia may cause:

  • Lethargy and fatigue
  • Weakness
  • Feeling cold
  • Feeling dizzy
  • Headaches
  • Shortness of Breath

Infections occur because of limited amounts of normal white blood cells or “Leukopenia” and limited amounts of normal neutrophils or “Neutropenia.”

Anemia is not the same as Acute Myeloid Leukemia Symptoms. Patients with AML Leukemia get infections that do not heal as fast as they used to or just won’t heal at all. There is then the possibility of catching one infection after another. Moreover, generalized symptoms may go along with the infection. Leukemia cells do not fight off the infection as a normal white blood cell does.

Infections can lead to:

  • Excess bruising and bleeding
  • Frequent or severe nosebleeds
  • Unusual bleeding, such as frequent nosebleeds and bleeding from the gums

The cancer cells in AML Leukemia are larger than normal white blood cells, and have trouble getting through tiny blood vessels.  When this happens, the cells clog up the blood vessels making it hard for oxygen-carrying RBCs to get to their destination: the tissues.  This condition is called “Leukostasis.” Although rare, it is a condition that needs emergency medical assistance and treatment.

Similarity of Symptoms with Stroke

Some signs and symptoms may mirror that of a stroke. An abundant number of leukemia cells can cause:

  • Headache
  • Weakness in one side of the body
  • Slurred speech
  • Confusion
  • Sleepiness

Patients with Acute Myeloid Leukemia often have several non-specific or generalized symptoms. Tests are advised to confirm the diagnosis. When in doubt, always consult a medical doctor.

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13 Aug

What is AML Leukemia?

Posted in AML Leukemia on 13.08.13 by Merlyn

aml leukemia

AML Leukemia (also known as acute myeloid leukemia) is a type of cancer that forms new white blood cells or WBCs. It is a cancer of the blood and bone marrow.

Acute Leukemia is also known by many other names including: acute granulocytic leukemia, acute myelocytic leukemia, acute myelogenous leukemia, and acute non-lymphocytic leukemia. Since it’s classified as an acute type of leukemia, it means that the disease can grow very quickly. If it’s not treated right away, the mortality rate is counted in just a few months.

How Does Acute Leukemia Symptoms Develop?

In order to further understand what Acute Myeloid Leukemia Symptoms is, let’s first understand what the lymphatic and circulatory (blood) systems are.

Any type of blood-forming cells can transform to a leukemia cell. When that happens, cells grow and divide to form many new cancer cells. Those newly developed cells attack the bone marrow and travel to the bloodstream. They then spread to other parts of your body, attacking the organs.

Parts of the Body That May Be Involved in AML Leukemia Development

  • Bone Marrow – these are the soft, spongy inner part of the bones, that can be found in backbones, pelvis, ribs, shoulder blades and skull. All blood cells are produced in the bone marrow that consists of blood-forming cells, blood stem cells, fat cells, and tissues that help develop the cells.
  • RBCs or Red Blood Cells – these are the carriers of oxygen from the lungs to tissues in various organs of the body. Carbon dioxide and cell waste products are also carried by Red Blood Cells. Not having enough RBCs can cause a person to feel tired, weak, and to experience shortness of breath.
  • WBCs or White Blood Cells -  these are protectors of our body. WBC fights off infections. There are 3 types of WBCs namely—granulocytes, monocytes, and lymphocytes, with each having a special role to play in protecting our bodies against infection.
  • Platelets – these break off from certain bone marrow cells and their main function is to clot blood by plugging holes in blood vessels that have been ruptured by cuts or bruises. Insufficient amount of platelets can cause a person to bleed or be bruised easily.

The Immune System

Your immune system is made up mainly of lymph tissues. The cell type that forms the lymph tissue is the lymphocyte (a type of white blood cell or WBC). They’re the front liners that fight different types of infections.

There is some discord among experts about the types of lymphocytes. Others state that there are three, while some state that there are only two. For the sake of comprehensiveness, we will mention all three.  However, note that two of these three types (B and T cells) also have multiple (sub)types. Those multiple types will not be discussed in detail.

Here are the three types of lymphocytes:

  1. B cells – these are a vital part of the immune system. They make the antibodies that combat antigens, or any substance that compromises the immune system.
  2. T cells – these have a central role in cell-mediated immunity. They orchestrate the immune system’s response to infected or malignant cells.
  3. NK or Natural Killer cells – these are tasked with keeping viral infections under control.

AML Leukemia M4 starts in the cells that are supposed to develop and mature in different types of blood cells. They first go into the bone marrow, but in most cases,  they start off or move directly to the blood stream, spreading to different parts of the body. Sometimes they spread to other parts of the body including but not limited to the brain, liver, lymph nodes, spleen, and the testicles.

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12 Aug

Getting to know Acute Myelogenous Leukemia

Posted in AML Leukemia on 12.08.13 by Merlyn

The most common acute leukemia affecting adults is Acute Myelogenous Leukemia. This is a cancer that affects bone marrow. Bone marrow is the tissue inside bones. It helps to form blood cells. This is a cancer of cells that would otherwise become white blood cells. The reason it is called acute is that it develops very fast. The reason it is called myelogenous is that it is seen affecting a specific type of blood cells, the myeloid cells.

Normally these cells mutate or evolve into myeloid, erythroid or megakaryocytic cells. But when one has this condition they are unable to differentiate into these. If a patient does not get treatment, the patient may die very fast. Usually a patient dies in a matter of six months to a year. They die from failure of bone marrow. Acute Myelogenous Leukemia is more common in men, than in women.

 

Risk Factors involved in Acute Myelogenous Leukemia

This is one of the most common types of AML leukemia observed in adults. Rarely seen in younger people especially those under the age of forty, it is also observed to affect men more than women. It is caused by abnormalities in cells in the bone marrow. These abnormal cells grow very fast. They eventually outgrow the healthy blood cells in numbers. Bone marrow usually is instrumental in helping the body to fight infections and immunity. Under this condition the bone marrow no longer functions as normal.

Due to this decrease in immunity, people affected with Acute Myeloid Leukemia Symptoms become more prone to infections. Blood does not clot easily, and bleeding is commonly observed. This is because of a decrease in the number of healthy blood cells in the body. Medical professionals too have a difficult time explaining what causes this cancer.

Certain factors have been observed among patients who have Acute Myeloid Leukemia Stages. Usually they all have blood disorders. Exposure to certain chemicals such as benzene and other harmful substances is common to people who have this condition. Exposure to radiation is also one of the risk factors.

Another observation is that people who have undergone certain medical procedures have an increased risk. People who have had an organ transplant or even chemotherapy are at an increased risk. Hereditary reasons are also an important factor. Certain people have it in their DNA to be more prone to developing Acute Myeloid Leukemia than others.

 

Symptoms Observed for AML Leukemia

Bleeding is the most common symptom that is observed in patients. People have signs of bleeding from the nose. Sometimes other sensitive tissues like the gums may bleed. Pain emanating from the bones and tenderness is also seen. The pain from the bones can be excruciating.

Feeling exhausted all the time with frequent bouts of fever is another symptom. In women heavy bleeding during menstruation and paleness of the skin is observed. In addition to exhaustion, shortness of breath often results. This shortness of breath can get worse when you exercise. Rashes on the skin and frequent lesions happen. Rapid weight loss is also common. In a few rare cases, swelling of the gums has been reported.

This type of leukemia is not easily detected due to the symptoms. The symptoms are common to many other common infections, so they go unnoticed. Acute Myelogenous Leukemia is usually detected during routine blood tests. There may also be other signs such as a swollen spleen. Swelling may also be observed in the liver or the lymph nodes.

If this condition has not been confirmed but a person shows the symptoms, a medical professional may recommend a blood test. The results of the blood test will be analyzed for several factors. Signs of anemia are looked for, as the platelets and red blood cell counts fall. Irregularities in white blood cell count are looked for. The white blood cell count may be abnormally high or even abnormally low.

 

Treatment of Acute Myelogenous Leukemia

Chemotherapy is usually involved in treating Acute Myelogenous Leukemia. There are several reasons for chemotherapy. It may be given to cure cancer. It may be given to prevent the spread of the disease. It may even be given to relieve patients of the pains caused by cancer.

There are several ways the chemicals are administered. They may be injected into the muscles or under the skin. They may be injected into an artery or a vein. They may be given as pills. They may even be injected into the spinal cord or the brain. Chemotherapy is usually given in cycles. It also has side effects.

People who are given chemotherapy for Acute Myeloid Leukemia show a few side effects. The reason is chemotherapy also kills healthy cells. The cells that are commonly attacked are those in the bone marrow, hair or the lining of the digestive system. This increases the risk of infection. Doctors usually advise patients to stay away from others. There is also an increased risk of bleeding, so people have to be careful with getting cuts. Some patients have also shown signs of mouth sores. People under chemotherapy need to eat a healthy diet as weight loss is also one of the side effects.

There are other treatments for this condition. A medical expert may also prescribe antibiotics. These are usually given to treat infections. Stem cell or bone marrow transplant may be prescribed. This is usually done after one round of chemotherapy. Anemia is a symptom of this cancer, so red blood cell transfusion may be administered. Bleeding is also a symptom, so platelet transfusions may be done.

Biopsy is done on bone marrow after treatment. If the biopsy shows that the sign of the cancer is absent, the patient is said to be in remission. Remission is not the same as a cure. But full remission happens in most patients. There are other factors that are involved in how well a patient recovers. Age is one factor. Overall health is another. Younger people who are overall healthy show better remission from this cancer and AML Leukemia Survival Rates.

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